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Structured assessment of frailty in multiple myeloma

Structured assessment of frailty in multiple myeloma as a paradigm of individualized treatment algorithms in cancer patients at advanced age



Life expectancy and incidence of cancer have substantially increased, the latter being closely interlinked to our longevity. Today, 617 million people are ≥65 years; by 2050, this number will have reached 1.6 billion, nearly 20% of the world’s population, and the number of "very old" (>80 years) will have more than tripled.1 This aging of the population involves enormous changes to patient care. For the moment, the most profound changes are to be seen in Japan, Europe and North America. Major risk factors associated with aging include cancer (also multiple cancers in a single patient), and cardiovascular and neurodegenerative diseases, all requiring long-term care. Therefore, especially high-income countries are obliged to meet the challenges.



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